In line with the mission of MRC and the principles by which the Unit was created, the current research activities are focused on the understanding of the mechanisms responsible for cell dysfunction and death, which are common to disease and toxic states. We study how cells, tissues and simple organisms react to different types of injury, triggered by environmental agents as well as by endogenous molecules. This integrated approach complements the scope of classical research in toxicology and it is likely to produce fundamental advances in biomedical science. Thus, the Unit's research does not address the mechanism of action of selected groups of chemicals, but generates fundamental knowledge on the pattern responses to injury within individual cells and organs. Such knowledge is essential to address emerging public health problems that may arise from exposure to toxic substances.
Research Laboratories
Post-transcriptional Control of Gene Expression
microRNA Regulation of Gene Expression
Molecular Mechanisms of Cell Death
Cell Death Regulation
In vivo Models of Disease and toxicity in the Nervous System
Apoptosis & Cancer
Toxicity and the DNA damage response
Cell Signalling
Neuronal model systems for studying neurotoxicity
Affiliated Programmes
Molecular Determinants of Apoptosis
Regulation of the Cytotoxic Response in Mature B-cells
Copyright Restrictions
All copyrights in this website, including logos, illustrations, photos, sound, scripts, animation and other material appearing on this website, otherwise known as "content", belong to the MRC Toxicology Unit or third parties authorising the MRC to use the copyrights.
Users must not reprint or electronically reproduce from the MRC Toxicology Unit website any graphic in whole or in part without the prior written permission of the MRC Toxicology Unit.
Users may download and save electronic documents, audio files and forms from the Website and print or listen to these for personal use, but such forms, files and documents remain the copyright of the MRC Toxicology Unit, 2013.